Cervical cancer (CC) is one of the most widely spread oncological pathologies that ranks second by the incidence in women in the world. Each year about 600 thousand of new CC cases are registered in the world with more than 250 thousand lethal outcomes. The virus nature of this cancer is confirmed by the World Health Organization and HPV is detected practically in 100 percent of cases of cervical precancer and cancer. Based on the frequency of detection of HPV genotypes from different grades of Cervical Intraepithelial Neoplasia (CIN Grades I-III), HPV genotypes are subdivided into High-risk HPV types (16, 18, 31 and 45), Intermediate-risk types (33, 35, 39, 51, 52, 56, 58, 59, and 68), and Low-risk types (6, 11, 42-44). Owing to the fact that the cervical cancer (CC) has a long development period and a fail-safe recognizable pre-clinic phase there is a possibility to detect and prevent the disease on its early stage.
The kit HPV High Risk Screen Real-TM Quant is an in vitro Real Time amplification test for quantitative detection of 12 types of HPV (16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59). It being known, that the parameter of viral load has a prognostic value and the viral load less than 10*5 HPV genomic equivalents in the swab or 10*3 genomic equivalents for 10*5 cells is considered as insignificant and indicates the presence of transitory infection, however such level of load may have a value only in cases of treatment monitoring. Viral load of more than 10*5 genomic equivalents for 10*5 cells is considered to be important with high significance and indicates the existence of dysplastic changes or high risk of their occurrence. Quantitative detection of viral load allows to evaluate the character of the infection and to make a forecast concerning the stage of the disease.
| Kit |
Description |
N. test |
Code |
 HPV 14 Screening & 16,18, 45 Typing Real-TM Quant  |
| Real Time PCR kit |
Real Time PCR kit for quantitative detection and genotyping of Human Papillomavirus types 16,18,45 and quantitative detection of HPV types 31, 33, 35, 39, 51, 52, 56, 58, 59, 66, 68 |
100 |
 V31-100/F FRT
|
|
| HPV High Risk Screen Real-TM Quant |
| Real Time PCR kit |
Real Time Amplification test for quantitative detection of Human Papillomavirus (16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59) |
100 |
V31-100/2FRT
TV31-100/2FRT
|
|
| HPV High Risk Screen Real-TM Quant 2X |
| Real Time PCR kit |
Real Time amplification test for quantitative detection of Human Papillomavirus (16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59) on two-channels devices |
100 |
V31-100/2FRT 2x
|
|
The kit HPV High Risk Typing Real-TM is an in vitro multiplex Real Time amplification test for qualitative detection and genotyping of Human Papillomavirus (16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59) in the urogenital swabs and biopsies. The kit HPV High Risk Typing Real-TM is based on two major processes: isolation of DNA from specimens and multiplex Real Time amplification of 4 tubes for each sample. Each tube contains primers directed against regions of three HPV types and beta-globine gene used as Internal Control.
| Kit |
Description |
N. test |
Code |
| HPV Genotypes 14 Real-TM Quant |
| Real Time PCR kit |
Real Time PCR Kit for quantitative detection and genotyping of Human Papillomavirus (16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66 and 68) |
100 |
V67-100FRT
|
|
|
|
| HPV Genotypes 21 Real-TM Quant |
| Real Time PCR kit |
Real Time PCR kit for identification, typing and quantification of Human Papillomavirus types low-risk (HPV 6, 11, 44) and high- risk (HPV 16, 18, 26, 31, 33, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66, 68, 73, 82) |
96 |
V21-100 FRT
|
|
